Cathedral of Santa Maria del Fiore and Piazza Duomo
Piazza Duomo and the group of buildings that form its cathedral complex gather some of Italy’s greatest artistic treasures into one relatively small area. As you tour the baptistery, the bell tower, the cathedral, and its museum, you’ll see some of the best-known masterpieces of art and architecture by the greatest artists of the Italian Renaissance — Ghiberti, Brunelleschi, Donatello, Giotto, and Michelangelo.
Battistero di San Giovanni (Baptistery of St. John)
From any angle, inside or out, the 12th-century octagonal baptistery is a consummate work of art. Its marble façade, the intricate mosaics of its interior, and the art works it holds all merit a place high on your list.
Palazzo Vecchio (Palazzo della Signoria)
History, art, and power echo in the opulent rooms and grand galleries of this fortress-like palace in the center of Florence. From here, the city/republic was ruled, and its powerful Medici family commissioned the leading artists and architects of the day to design and decorate their offices and apartments.
Uffizi Palace and Gallery
Few would argue the Uffizi’s place among the handful of world’s top art museums. Its collections are simply staggering in their diversity and quality, and even if art is not your main interest, you should see the highlights of the paintings here.